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Angiocentric T-cell Lymphoma of the Mid-face: A Case Report

Issue: Vol.2, No.2 - January 2003

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Article Type: Manuscript

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  1. Dr G.M. Masrani
    MD (Pathology)
    Department of ENT & Head, Neck Surgery, Masina Hospital
  2. Rehan A Kazi

Considerable confusion and controversy surround the diagnosis of patients with destructive lesions of the nose and mid-face. Advances in pathologic analysis of tissues have been accompanied by an increased understanding of the different diseases that can cause granulomatous and necrotic destruction of the mid-face. We report the presentation of a 35 yr old patient with progressive destruction of the soft tissues of the nose and paranasal sinuses. Biopsy of the lesion revealed lymphoproliferative cellular component and an angiocentric growth pattern consistent with angiocentric T-cell lymphoma. Patient was subjected to combined modality treatment of surgical debridement followed bu radiotherapy and multi-drug chemotherapy. He tolerated the regimen fairly well and is currently in remission 12 months later.

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