Comparison of Whole Body Scintigraphy with Tc-99m-Methoxyisobutylisonitrile and Iodine-131 Na in Patients with Differentiated Thyroid Cancer

Issue: Vol.2, No.2 - January 2003

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Article Type: Manuscript

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  1. Dr Khalid Al-Saleh
    Department of Radiation Oncology, Kuwait Cancer Control Center, Ministry of Public Health,
  2. Al-Shammeri Iman
  3. Abdul Naseer Mohammed
  4. H S Hooda
  5. Reham Safwat
  6. Al-Mohannadi Shihab

In this study we compared whole body scintigraphy Tc-99M-methoxyisobutylisonitrile (MIBI) and Iodine-131 NA(131I) for detection of residual and/or metastatic disease in well differentiated thyroid carcinoma.

Methods: MIBI and I-131 scans were obtained in 60 patients. TSH measurements were done in all the patients prior to scintigraphy.

Results: Out of 60 patients, for whom both I-131 and MIBI scans were positive in 59 (98.3%) patients, whereas MIBI scans were positive in only 17 (27%) patients. There was only one patient in which I-131 scan was negative and MIBI scan was positive.

Conclusion: I-131 scintigraphy still remains the best way to successfully detect residual/metastatic disease in differentiated thyroid carcinoma.

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